Jul. 08': Immunizable diseases and Down syndrome

People with Down syndrome (DS) are especially infection-prone, particularly during childhood.
The main reason is an association of DS with multifactorial primary immune deficiency.
Many of these conditions are immunizable, but studies of vaccination and DS are few and do not
include recent formulations. While awaiting remediation of this gap, the present state of knowledge is that available vaccines are safe and effective for
people with DS, though the possibility that response may be lower than average means that strict compliance with immunization schedules is required to ensure effectiveness.

Keywords: Down syndrome. Active immunization.
Vaccination. Passive immunization.

Jul. 08': Arthritis in a patient with Down syndrome

We present the case of a 35-year-old patient with long-standing polyarthritis and Down syndrome. Both of these conditions share a clinical and radiological sign in common, namely,
atlantoaxial subluxation, though probably due to different causes.
We discuss this rare combination of both conditions as well as challenges for treatment.

Keywords: Down syndrome. Rheumatoid arthritis.

Jul. 08': Psychomotor development in children with Down

Children with Down syndrome have unique defining traits with a specific bearing on their psychomotor development. Brain characteristics, musculoskeletal abnormalities and associated medical conditions are the most significant factors that affect their psychomotor development, both in terms of milestone timing and in the quality of movements. The main aim of Early Intervention is to optimise and support the child’s development, fostering their capabilities and taking on board their individuality. Physiotherapy is offered primarily as a preventive service. Children are given the chance to experience appropriate movement, by setting optimum patterns and preventing misaligned ones. Parents and significant others in the child’s environment are also given advice.

Keywords: Down syndrome. Psychomotor development.
Early intervention. Physiotherapy.