Determination of biological markers in the cholinergic systems of patients with DS

Lead researcher: Dr. M. Dierssen, Hebrew University of Jerusalem. "Genes and disease" program, Centre de Regulació Genòmica (Centre for Genomic Regulation).

The study focuses on determining the state of the cholinergic system in patients with DS and establishing its relationship with cognitive impairment. Samples from patients with DS will be analyzed at the Hebrew University of Jerusalem by assessing the catalytic activity of cholinergic system enzymes.